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Launch price: from €29.90 per box. Free delivery from 2 boxes.

FRENDEESIT
The Layer Nutrition Beta-Blockers bottle, 30 capsules.
You take a beta-blocker. And your night-time melatonin: who thinks about it?
The comparison. See the difference.
A single dose of propranolol or atenolol reduced night-time melatonin by 80 to 86%. 15 healthy volunteers, overnight urine measurement. Carvedilol changed nothing. Stoschitzky, Eur J Clin Pharmacol, 1999.
1 mg, shortly before bedtime. Melatonin contributes to the reduction of time taken to fall asleep.
We add it to your beta-blocker, never in its place. Melatonin, magnesium and B6, one capsule at bedtime.
We designed it for beta-blockers. It's not a multivitamin aimed at everyone.
What each capsule contains. Melatonin 1 mg. Magnesium 100 mg.
In figures. What's really inside.
How to take it. One capsule shortly before bedtime, with a glass of water.
And the next day? Magnesium and B6 contribute to the reduction of tiredness and fatigue.
Your beta-blocker does its job. Do yours. Layer Nutrition Beta-blockers.
BB01 · Food supplement

Layer Nutrition Beta-Blockers

For people who take a beta-blocker

1 mg of melatonin, which contributes to the reduction of time taken to fall asleep, with magnesium and vitamin B6. One capsule shortly before bedtime, on top of your beta-blocker.

What it brings you

  • Contributes to the reduction of time taken to fall asleep (melatonin 1 mg, at bedtime)
  • Contributes to the reduction of tiredness and fatigue (magnesium, vitamin B6)
  • Contributes to normal muscle function and to the normal functioning of the nervous system (magnesium)

Bisoprolol, atenolol, metoprolol, nebivolol, propranolol and five others. If your medicine contains one of these, this formula is yours. Check my medicine

QuantityLaunch price
Frequency
Total€36.90+ €4.90 deliveryA single shipment.

Be notified when BB01 launches

  • Free delivery from 2 boxes
  • 30 capsules, 30 days
  • Full composition on the label

30 plant-based capsules · 1 capsule a day · Food supplement

01Composition

What each capsule contains.

Values per capsule. The full list of ingredients is on the label.

Formulation lead: Evangelia Thoukididou, nutritionist specialising in nutrient-drug interactions.

1mg

Melatonin

Melatonin

It contributes to the reduction of time taken to fall asleep. The effect is obtained by taking 1 mg shortly before bedtime.

100mg

Magnesium

Magnesium bisglycinate

It contributes to the reduction of tiredness and fatigue, to normal muscle function and to the normal functioning of the nervous system.

100 mg of elemental magnesium per capsule, as bisglycinate.

1,4mg

Vitamin B6

Pyridoxal-5′-phosphate

It contributes to the reduction of tiredness and fatigue and to the normal functioning of the nervous system.

100% of the nutrient reference value

02Why this formula

What research has measured.

A randomised trial measured the melatonin produced overnight by healthy volunteers after a single dose of certain beta-blockers.

Published measurement · Randomised, crossover, placebo-controlled trial · 15 healthy volunteers

−80 to −86%

Melatonin produced overnight, measured in urine, after a single dose of propranolol or atenolol. Carvedilol changed nothing.

Stoschitzky K. et al., Eur J Clin Pharmacol, 1999; 55(2): 111-115.

Compared with placebo, 80% less after propranolol and 86% less after atenolol (S-enantiomers). A single dose in healthy volunteers, not ongoing treatment.

Fig. 1Simplified diagram. A published measurement is not a demonstrated benefit of a supplement.
03Your treatment

The medicines concerned.

BB01 is for people who take one of these beta-blockers. It does not replace your treatment and does not change it.

This list shows the most common names and is not exhaustive. If yours is not here, look it up in the atlas: it brings together the 188,627 medicines we have indexed.

Check my medicine in the atlas
04Directions for use
The Layer Nutrition Beta-blockers bottle on a bedside table, next to a lit lamp.

One capsule a day, shortly before bedtime, with a glass of water. No time gap needed with your beta-blocker.

Your routine

  1. Day 1

    Your first capsule, shortly before bedtime.

  2. By appointment

    With the subscription, one of our coaches reviews your meals with you, taking your treatment into account.

  3. Day 30

    Your first box runs out. With the subscription, the next shipment leaves at the frequency you chose. Without a subscription, you order the next one whenever you wish.

Food supplement. Never change your treatment without your doctor’s advice.

  • Recommended daily dose: one capsule.
  • Melatonin contributes to the reduction of time taken to fall asleep. The beneficial effect is obtained by consuming 1 mg of melatonin close to bedtime.
  • Do not exceed the stated recommended daily dose.
  • Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.
  • Keep out of the reach of young children.
  • Store away from heat and moisture.

The health claims for our formulas appear in the list of Regulation (EU) No 432/2012.

05Questions

Frequently asked questions about BB01

Why melatonin with a beta-blocker?

In healthy volunteers, a dose of propranolol or atenolol reduced night-time melatonin production (Stoschitzky, 1999). Melatonin contributes to the reduction of time taken to fall asleep, at 1 mg taken shortly before bedtime: that is the dose in the capsule.

When should I take it?

Take it shortly before bedtime, with a glass of water. Avoid driving in the hours that follow.

Does it replace my treatment?

No. It is a food supplement, taken on top of your treatment. Never change the dose of your beta-blocker and never stop it abruptly without your doctor.

Bisoprolol, atenolol, metoprolol: is it the same box?

Yes. The formula is taken with each of the beta-blockers on the list: bisoprolol, atenolol, metoprolol, nebivolol, propranolol and the others. Changing molecule changes nothing about the box.

What exactly does the capsule contain?

It contains melatonin, magnesium bisglycinate, vitamin B6 and a plant-based shell. The full list of ingredients is on the label.

Launch price€36.90